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EPHB2 — IQGAP1

Text-mined interactions from Literome

Roy et al., Mol Cell Biol 2005 (MAP Kinase Signaling System) : Similarly, ERK1 promoted MEK binding to IQGAP1 , but either MEK protein altered the association between IQGAP1 and ERK ... In addition, both knockdown and overexpression of IQGAP1 reduced EGF stimulated activation of MEK and ERK
Ren et al., Proc Natl Acad Sci U S A 2007 : We previously documented that IQGAP1 binds ERK and MAPK kinase ( MEK ) and regulates EGF stimulated MEK and ERK activity
Nojima et al., Nat Cell Biol 2008 (MAP Kinase Signaling System) : Thus, IQGAP3 is necessary and sufficient for driving cell proliferation and ERK acts downstream of IQGAP3
Casar et al., Mol Cell Biol 2009 : To phosphorylate the EGFr, ERK1/2 activated at lipid rafts require the participation of IQGAP1
Sbroggiò et al., Cardiovasc Res 2011 (Disease Models, Animal...) : IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload