Sivalenka et al., Eur J Immunol 2008
(Anaphylaxis) :
Key FcepsilonRI signal transduction events like activation of LAT by phosphorylation, activation of Akt/PKB and of p38 MAP kinase are reduced in SWAP-70 ( -/- ) BMMC, but ERK is strongly hyperactivated
Roget et al., J Immunol 2008
:
We finally show that the positive effect of NTAL on Akt phosphorylation and mast cell survival requires LAT