Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Yacoub et al., Mol Cancer Ther 2008 (Glioblastoma) : In GBM6 cells, GST-MDA-7 ( 30 nmol/L ) transiently activated p38 mitogen activated protein kinase, which was modestly protective against JNK1-3 induced toxicity, whereas GST-MDA-7 ( 300 nmol/L ) caused prolonged intense p38 mitogen activated protein kinase activation, which promoted cell death
Lu et al., Anat Rec (Hoboken) 2013 (Carcinoma, Hepatocellular...) : We considered that TFPI-2 reduces 5-FU resistance in BEL-7402/5-FU cells, and the mechanism appears to involve p38 mediated downregulation of drug resistance gene expression such as MDR1, LRP, MRP1, GST-p , and ERCC1