Gene interactions and pathways from curated databases and text-mining

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BIK — CASP12

Text-mined interactions from Literome

Zhu et al., Oncogene 2005 (Colonic Neoplasms...) : To characterize the mechanisms of apoptosis induction by proteasome inhibitors, we examined levels of Bcl-2 protein family members ( Bik/NBK , Bax, Bak, Bcl-2, and Bcl-XL ), release of cytochrome c, and activation of caspase-9 and -3 in human colon cancer cell lines DLD1, LOVO, SW620, and HCT116 ; human lung cancer cell line H1299 ; and human ovarian cancer cell line SKOV3 after they were treated with bortezomib
Zhao et al., Biochem Biophys Res Commun 2007 (Carcinoma, Hepatocellular) : In this study, we show that caspase-12 was activated by BIK