Gene interactions and pathways from curated databases and text-mining

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CCL2 — PLG

Text-mined interactions from Literome

Carulli et al., Arthritis Rheum 2005 (Scleroderma, Systemic) : In these cultures, specific inhibition of CCL2 or CCR2 attenuated the overexpression of alpha-SMA, but not CTGF or plasminogen activator inhibitor 1
Sheehan et al., J Neurosci 2007 (Neurodegenerative Diseases) : Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice
Li et al., Mol Immunol 2010 : Additionally, we show that plasmin induced the phosphorylation of STAT3 is similar to that of IL-6 and IL-31, and protease activated receptor 1 does not affect plasmin induced cytokine MCP-1 release in human monocytes ... Finally, our data demonstrate that plasmin triggers the production of MCP-1 in macrophages in vivo