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STAT1 — TGFB1

Pathways - manually collected, often from reviews:

• NCI Pathway Database IL27-mediated signaling events: TGFB1 (TGFB1) → STAT1 (dimer) complex (STAT1) (transcription, activates)
  Stumhofer et al., Nat Immunol 2006*, Batten et al., Nat Immunol 2006*
  Evidence: mutant phenotype, other species

Text-mined interactions from Literome

Park et al., J Immunol 2005 : Consistent with a direct role for Shp-1, TGF-beta1 's inhibition of IFN-gamma induced Stat1 phosphorylation was sensitive to the general PTP inhibitor pervanadate
Takaki et al., Genes Cells 2006 : We also found that TGF-beta1 directly inhibited IFN-gamma induced STAT1 activation by reducing STAT1 tyrosine phosphorylation ... Reduced activation of STAT1 by TGF-beta1 was abrogated by the mutation in the IFNGR1 in which the serine residues of potential sites of phosphorylation by TGF-betaRI were replaced by alanine residues