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BACE1 — SUMO1

Text-mined interactions from Literome

Fang et al., Neuro Endocrinol Lett 2011 : SUMO negatively regulates BACE expression ... The effect of SUMO on the promoter activity and mRNA expression of BACE gene was investigated to find the connection between sumoylation and APP processing ... Endogenous BACE mRNA level was also negatively regulated by the induction of SUMO proteins ... SUMO negatively regulates the BACE expression and SP1 is involved in the process
Yun et al., Neurobiol Aging 2013 (Alzheimer Disease...) : In this report, we found that small ubiquitin-like modifier (SUMO)-1 interacts with the dileucine motif of BACE1 and regulates the level of BACE1 protein