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CRK — TP53

Text-mined interactions from Literome

Bulavin et al., Mol Cell Biol 2003 (MAP Kinase Signaling System) : Inhibition of p38 mitogen activated protein kinase ( MAPK ) activation correlated with the deregulation of p53 activation, and both a p38 MAPK chemical inhibitor and the expression of a dominant negative p38alpha inhibited p53 activation in the presence of H-ras in wild-type MEF
Kool et al., Oncogene 2003 (MAP Kinase Signaling System) : Using specific inhibitors, we found that the ATM- and Nibrin1 dependent activation of ATF3 does neither require p53 nor reactive oxygen species, but is dependent on the p38 and JNK MAPkinases
Kim et al., Gastroenterology 2005 (MAP Kinase Signaling System) : We investigated the role of p53 dependent pathways and p38 mitogen activated protein kinase ( p38 ) in toxin A-induced colonocyte apoptosis
Hou et al., Cancer Lett 2008 (Osteosarcoma) : In addition, ASK1, p38 and JNK siRNA reduced HBI induced p53 phosphorylation and Bax expression
Liu et al., Cardiovasc Res 2011 (MAP Kinase Signaling System...) : Oestrogen prevents cardiomyocyte apoptosis by suppressing p38a mediated activation of p53 and by down regulating p53 inhibition on p38ß
Park et al., Mol Carcinog 2012 (Colonic Neoplasms...) : HFD feeding increased tumor tissue levels of Ki67, cyclin A, cyclin D1, CDK2, Bcl-xL, and Bcl-2 ; reduced p53 levels and TUNEL positive apoptotic cells ; increased the levels of CD45, CD68, CD31, VEGF, P-VEGF receptor-2, iNOS, and COX-2 as well as hemoglobin content ; and increased the levels of HIF-1a, P-STAT3-Y705, P-STAT3-S727, P-I?B-a, P-p65, p65, P-c-Jun, P-Akt, P-ERK1/2, P-p38 , and P-SAPK/JNK