Luftig et al., Proc Natl Acad Sci U S A 2004
:
Thus, LMP1 induces typical canonical IKKbeta/IKKgamma dependent, atypical canonical IKKbeta-dependent/IKKgamma independent, and noncanonical NIK/IKKalpha dependent NF-kappaB activations ; NIK/IKKalpha dependent NF-kappaB activation is principally mediated by the LMP1 TRAF binding site
Boehm et al., Proc Natl Acad Sci U S A 2010
:
These data provide further evidence of the essential role for NEMO in LMP1 TES2 NF-?B activation and highlight the importance of unique domains within NEMO for sensing distinct NF-?B stimuli