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DYRK1B — MAP2K3

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: DYRK1B → Complex of DYRK1B-MAP2K3 (directlyIncreases, DYRK1B/MAP2K3 Activity) Lim et al., J Biol Chem 2002*
  Evidence: Mirk co-immunoprecipitated with the MAPK kinase MKK3, an upstream activator of p38. MKK3 enhanced Mirk kinase activity and the transcriptional activation of HNF-1alpha by Mirk
• OpenBEL Selventa BEL large corpus: HNF1A → Complex of DYRK1B-MAP2K3 (increases, DYRK1B/MAP2K3 Activity) Lim et al., J Biol Chem 2002*
  Evidence: Mirk co-immunoprecipitated with the MAPK kinase MKK3, an upstream activator of p38. MKK3 enhanced Mirk kinase activity and the transcriptional activation of HNF-1alpha by Mirk

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: DYRK1B — MAP2K3 (in vivo) Lim et al., J Biol Chem 2002*
• IRef Innatedb Interaction: DYRK1B — MAP2K3 (unknown, -) Lim et al., J Biol Chem 2002*
• IRef Intact Interaction: DYRK1B — MAP2K3 (physical association, anti bait coimmunoprecipitation) Lim et al., J Biol Chem 2002*
• IRef Intact Interaction: DYRK1B — MAP2K3 (phosphorylation reaction, protein kinase assay) Lim et al., J Biol Chem 2002*