Chen et al., Kidney Int 2002
(MAP Kinase Signaling System) :
The previously identified basal control element-1 ( BCE-1 ) site, but not Sp1 contributes to basal CTGF promoter activity
Holmes et al., J Biol Chem 2003
(Scleroderma, Systemic) :
Constitutive connective tissue growth factor expression in scleroderma fibroblasts is dependent on Sp1 ... Blocking Sp1 activity reduces the elevated, constitutive levels of CTGF promoter activity and protein expression observed in SSc fibroblasts