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ERBB2 — FAS
Text-mined interactions from Literome
Silva et al., Oral Oncol 2004
(Carcinoma, Squamous Cell...) :
Taken together, the results presented here suggest that
ErbB2 regulates
FAS expression in HNSCC and point out Ki-67 as a useful prognostic marker for these tumors
Weng et al., Toxicol Appl Pharmacol 2007
(Breast Neoplasms...) :
Furthermore, treatment with kinase inhibitors of EGFR and ErbB-2 suggested that
EGFR/ErbB-2 activation was
involved in EGF induced
FAS expression ... The PI 3-kinase inhibitors and tyrosine kinase inhibitors of EGFR and
ErbB-2 also
reduced constitutive
FAS expression
Lokeshwar et al., Cancer Res 2010
(Neoplasm Invasiveness...) :
4-MU
induced caspase-8, caspase-9, and caspase-3 activation, PARP cleavage, upregulation of Fas-L,
Fas , FADD and DR4, and downregulation of bcl-2, phosphorylated bad, bcl-XL, phosphorylated Akt, phosphorylated IKB, phosphorylated
ErbB2 , and phosphorylated epidermal growth factor receptor