Gene interactions and pathways from curated databases and text-mining

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RASSF1 — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Tian et al., PloS one 2011 : Moreover, p53 binding to the promoter down-regulated RASSF1A expression
Lei et al., Mol Med Report 2013 : HPV16 infection regulates RASSF1A transcription mediated by p53 ... Similarly, knockdown of endogenous HPV16-E6 in SiHa cells with RNA interference ( RNAi ) led to downregulation of RASSF1A mediated by p53 and the subsequent induction of apoptosis ... These findings collectively suggest that HPV16 infection regulates p53 mediated RASSF1A expression and suppresses apoptosis