Gene interactions and pathways from curated databases and text-mining

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TP53 — TSC2

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Feng et al., Cancer Res 2007 (Cell Transformation, Neoplastic) : The regulation of AMPK beta1, TSC2 , and PTEN expression by p53 : stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways
Lee et al., EMBO J 2007 (Hamartoma...) : Thus, loss of TSC1 or TSC2 , the negative regulators of mTOR, results in dramatic accumulation of p53 and apoptosis in response to stress conditions