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JUN — MAP3K13
Text-mined interactions from Literome
Sondarva et al., Cell Res 2010
:
Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase that is activated by tumor necrosis factor-alpha (TNF-alpha) and specifically
activates c-Jun N-terminal kinase (JNK) on TNF-alpha stimulation
Jin et al., Dev Biol 2013
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Second,
MAP3K1 potentiated AP-2a expression and SRF and
AP-1 activity, but its target genes were enriched for binding motifs of AP-2a and SRF, and not AP-1, suggesting the existence of novel MAP3K1-AP-2a/SRF modules in gene regulation