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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CA8 — CASP6

Text-mined interactions from Literome

Lu et al., Lung Cancer 2004 (Adenocarcinoma...) : Interestingly, ectopic CA-RP VIII expression markedly reduced caspase-3 activity induced by serum starvation and anti-cancer agents in PC-9 cells
Van Geelen et al., Drug Resist Updat 2004 (Colorectal Neoplasms) : Additional intracellular factors leading to TRAIL-resistance affect the caspase 8/c-FLIP ratio, such as loss of caspase 8 and caspase 10 due to mutations or gene methylation, CARP dependent degradation of active caspase 8 and changes in caspase 8 or c-FLIP expression levels