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MMP14 — STAT3
Text-mined interactions from Literome
Udayakumar et al., Prostate 2004
(Prostatic Neoplasms) :
Further, expression of dominant negative
STAT3 inhibited the FGF-1 induced transactivation of the human
MT1-MMP 7.2-kb promoter ... From these data, we conclude that FGF-1
induces MT1-MMP expression in prostate carcinoma cells through a transcriptional mechanism mediated through the FGFR and the transcription factor,
STAT3
Akla et al., Exp Cell Res 2012
(Inflammation) :
Given MSC chemotaxis and cell survival are regulated, in part, by the membrane type-1 matrix metalloproteinase ( MT1-MMP ), an MMP also involved in transducing NF-?B intracellular signaling pathways, we tested whether
STAT3 regulation by
MT1-MMP may also contribute to the expression balance of COX-2 in MSC