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CD27 — RELA
Text-mined interactions from Literome
Nakano et al., Proc Natl Acad Sci U S A 1999
:
Activation of either
NF-kappaB or c-Jun NH ( 2 ) -terminal kinase/stress activated protein kinase by tumor necrosis factor,
CD27 , and CD40 was not abrogated in traf5 ( -/- ) mice
Akiba et al., J Biol Chem 1998
:
CD27 , a member of the tumor necrosis factor receptor superfamily,
activates NF-kappaB and stress activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB inducing kinase ... Here we demonstrate that overexpression of
CD27 activates
NF-kappaB and stress activated protein kinase ( SAPK ) /c-Jun N-terminal kinase (JNK) ... Co-transfection of a dominant negative TRAF2 or TRAF5 blocked
NF-kappaB and SAPK/JNK activation
induced by
CD27
Yamamoto et al., J Immunol 1998
:
In the present study we demonstrate that overexpression of
CD27 in 293 cells
induces a low level of
NF-kappaB activation, and the ligation of the receptor by its corresponding ligand ( CD70 ) augments this signal dramatically