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MYLIP — STMN1

Text-mined interactions from Literome

Chen et al., Oncogene 2013 (Melanoma) : We now report that STMN1 is upregulated during the progression of melanoma relative to benign nevi, and that STMN1 is directly regulated by miR-193b ... Using an experimental cell culture approach, overexpression of miR-193b using synthetic microRNAs repressed STMN1 expression, whereas inhibition of miR-193b with anti-miR oligos increased STMN1 expression in melanoma cells ... The use of a luciferase reporter assay confirmed that miR-193b directly regulates STMN1 by targeting the 3'-untranslated region of STMN1 mRNA ... Taken together, our study suggests that downregulation of miR-193b may contribute to increased STMN1 expression in melanoma, which consequently promotes migration and proliferation of tumor cells
Wang et al., PloS one 2012 (Breast Neoplasms...) : MiR-101 is involved in human breast carcinogenesis by targeting Stathmin1