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ICOSLG — IL10

Text-mined interactions from Literome

Wahl et al., J Am Soc Nephrol 2002 : Interestingly, interleukin-2 production by T cell hybridomas after antigen presentation by TEC was enhanced by blocking antibodies to B7RP-1 and ICOS
Witsch et al., Eur J Immunol 2002 : Interaction of ICOS with ICOS-L strongly promoted IL-10 secretion, whereas the CD28/B7 pathway acted as a potent attenuator of IL-10 release
Vermeiren et al., J Immunol 2004 : Suppression was not mediated by IL-10 and did not require ICOS-ICOS ligand interaction, but depended on cell-cell contact
de Haij et al., Kidney Int 2005 : Stimulation with interferon-gamma (IFN-gamma) resulted in increased expression of B7-H1, whereas ICOS-L expression was marginally increased upon stimulation with CD40L, with no effect of interleukin ( IL-1 ), IL-17, or tumor necrosis factor-alpha (TNF-alpha)
Scholz et al., J Am Soc Nephrol 2008 (Glomerulonephritis) : These findings demonstrate that renal DCs exert a renoprotective effect in nephrotoxic nephritis, possibly by expressing ICOS-L and/or by inducing IL-10 in infiltrating CD4 ( + ) Th1 cells
Colvin et al., Hum Immunol 2009 : These findings implicate ICOSL induced IL-10 , but not IDO in the regulation of BM-derived pDC function
Tuettenberg et al., J Immunol 2009 (Common Variable Immunodeficiency) : Furthermore, ICOS/ICOS ligand interaction stabilizes IL-10R expression on T cells and thus renders them sensitive to IL-10 effects
Ogata et al., Int Immunol 2013 : Plasmacytoid dendritic cells have a cytokine producing capacity to enhance ICOS ligand mediated IL-10 production during T-cell priming