Gene interactions and pathways from curated databases and text-mining

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IL2 — KIR3DL1

Text-mined interactions from Literome

Kogure et al., Ann Rheum Dis 2001 (Arthritis, Rheumatoid) : Therefore, KIR expression on lymphocytes in patients with RA, and the regulation of KIR expression by interleukin 2 (IL2) in RA was investigated ... The reduced induction of KIR expression in response to IL2 may provide insight into the reason for the high susceptibility of patients with RA to microbial infection
Chrul et al., Mediators Inflamm 2006 : In the present study, we analyze the modulatory effect of IL-2 alone or a combination of IL-12 with IL-18 on surface expression of killer cell immunoglobulin-like receptors KIR2DL1, KIR2DL2 , and KIR3DL2 in NK cells
Presnell et al., Genes Immun 2013 : IL-2/IL-15 activate the human clonally restricted KIR3DL1 reverse promoter ... Here we show that interleukin (IL)-2 and IL-15, cytokines critical for NK cell development and maintenance, greatly stimulated KIR3DL1 reverse promoter activity, but not forward promoter activity