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FGF2 — MYOG

Text-mined interactions from Literome

Layne et al., Exp Cell Res 1999 : Tumor necrosis factor-alpha and basic fibroblast growth factor differentially inhibit the insulin-like growth factor-I induced expression of myogenin in C2C12 myoblasts ... These results indicate that both TNF-alpha and bFGF inhibit myogenin expression but differentially influence myoblast proliferation
Fuentealba et al., J Biol Chem 1999 : Reduced expression of syndecan-3 resulted in a 13-fold decrease in sensitivity to FGF-2 dependent inhibition of myogenin expression
Tortorella et al., J Biol Chem 2001 : However, these factors have opposing roles with respect to differentiation ; insulin-like growth factor-1 enhances muscle cell differentiation, whereas bFGF inhibits the expression of the muscle-specific transcription factors MyoD and myogenin
Li et al., Cell 1992 : A myogenin mutant lacking the PKC phosphorylation site is not repressed by FGF , confirming this site as a molecular target for FGF dependent repression of muscle transcription
Magri et al., Adv Exp Med Biol 1991 : All of these agents affect the expression of myogenin , one of the recently discovered family of myogenesis controlling genes, and TGF-beta and FGF inhibit the expression of MyoD1 as well
Larraín et al., J Biol Chem 1998 : Analysis of the induction of a myogenin promoter-driven reporter revealed that syndecan-1 expression resulted in a 6-7-fold increase in sensitivity to bFGF dependent inhibition of myogenin expression