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JUN — RNF19A
Text-mined interactions from Literome
Oren et al., Mol Cell Biol 1999
:
Depolymerization of the cytoskeleton activates JNK and
p38 mitogen activated protein kinase and
induces c-Jun expression by a signaling pathway that depends on tyrosine kinase activity
Cohen et al., Biochem Pharmacol 2000
(Arteriosclerosis...) :
Although other analogues inhibited DNA synthesis, they affected neither ERK1 activation nor
p38/stress activated protein kinase 2 or
Jun N-terminal kinase 1 activation
Maeda et al., Mol Cell Endocrinol 2003
:
SB203580, a specific inhibitor of
p38 mitogen activated protein ( MAP ) kinase, and SP600125, a specific
inhibitor of
c-Jun N-terminal kinase (JNK) , also reduced the induction by both PDGF-BB and bFGF
Silvers et al., Neoplasia (New York, N.Y.) 2003
(Skin Neoplasms) :
These results demonstrated that activation of both JNK and
p38 play critical role in UVA mediated
AP-1 transactivation and c-Fos expression in these human keratinocyte cells
Chun et al., Carcinogenesis 2004
:
In order to clarify the
roles of
p38 and ERK in TPA induced
AP-1 activation, we utilized the pharmacologic inhibitors of these enzymes
Welsh et al., Infect Immun 2004
(MAP Kinase Signaling System) :
Increases in
c-Jun N-terminal kinase/stress
activated protein kinase and
p38 activity in monocyte derived macrophages following the uptake of Legionella pneumophila
Gao et al., Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2006
:
ERK and JNK, but not
p38 ,
mediated benzo ( a ) pyrene induced cell cycle changes by
AP-1 transactivation in HELF
Tirumurugaan et al., Am J Physiol Lung Cell Mol Physiol 2007
(MAP Kinase Signaling System) :
EMSAs confirmed the
role of
p38 and JNK in mediating NF-kappaB and
AP-1 activation
Jiao et al., Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2007
:
JNK and ERK signaling pathways, but not
p38 pathway
regulate B ( a ) P-induced
c-Jun activation in HELFs
Irarrazabal et al., J Biol Chem 2008
:
Thus,
AP-1 is part of the TonEBP/OREBP enhanceosome, and its role in high NaCl induced activation of TonEBP/OREBP may
require p38 activity
Yang et al., Atherosclerosis 2010
:
N-acetylcysteine, SP600125 ( JNK inhibitor ) and SB203580 (
p38 MAPK inhibitor )
attenuated TNF-alpha induced DNA binding activities of both
AP-1 and NF-kappaB
Liu et al., Int J Biochem Cell Biol 2010
:
Taken together, our data indicate that Fas/FasL up-regulation in piceatannol treated U937 cells is elicited by Ca ( 2+ )
/p38alpha MAPK mediated
activation of
c-Jun and ATF-2, and suggest that autocrine Fas mediated apoptotic mechanism is involved in piceatannol induced cell death
Son et al., Oncol Rep 2010
(Melanoma, Experimental) :
Ethanol extract of Lycoris radiata induces cell death in B16F10 melanoma via
p38 mediated
AP-1 activation
Ferreiro et al., J Biol Chem 2010
:
In addition,
p38 recruitment to the osmoinducible gene Cox2 and the TNFa target gene IL8 is
mediated by the transcription factors
AP1 and NF?B, respectively
Butoi et al., Biochim Biophys Acta 2011
:
Monocyte-SMC interaction induced the phosphorylation of
p38MAPK and
activation of
AP-1 transcription factor
Tan et al., J Cell Physiol 2012
:
Moreover, CCN3 induced c-Jun translocation into the nucleus, and the binding of c-Jun to the
AP-1 element on the BMP-4 promoter were both
inhibited by specific inhibitors of the ILK,
p38 , and JNK cascades
Saadane et al., Journal of inflammation (London, England) 2011
:
This was associated with enhanced phosphorylation of
p38 , ERK1/2 and JNK and increased
activation of
AP-1