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Kim et al., Cancer Lett 2003
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Transient expression and electrophoretic mobility shift assays with NF-kappaB binding sites revealed that BPA reduced the levels of the LPS induced NF-kappaB transcription factor complex
Lee et al., J Vet Sci 2007
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Further study of the mechanism showed that BPA significantly activated extracellular signal regulated kinase ( ERK ) but inhibited anti-apoptotic nuclear factor kappa B (NF-kappaB) activation
Lee et al., J Neurosci Res 2008
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BPA activated phosphorylation of extracellular signal regulated kinase ( ERK ) and c-Jun N-terminal kinase (JNK), and nuclear translocation of nuclear factor (NF)-kappaB Wang et al., Toxicol Lett 2010
(Osteoarthritis, Knee) :
In this study, we investigated the effects of E2 and BPA on nitric oxide ( NO ) production, NF-kappaB activation, and MMP-1 expression in chondrosarcoma SW1353 cells and primary human osteoarthritic chondrocytes