Gene interactions and pathways from curated databases and text-mining

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PLD1 — TP53

Text-mined interactions from Literome

Hui et al., Mol Cell Biol 2004 : PLD1 stimulated increases in MDM2 expression and suppression of p53 activation were blocked by inhibition of mTOR and the mitogen activated protein kinase pathway
Hui et al., Oncogene 2006 (Breast Neoplasms) : Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D ... We report here that the mutant p53 in MDA-MB-231 cells is stabilized by the elevated PLD activity in these cells