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TP53 — XPC

Text-mined interactions from Literome

Amundson et al., Cancer Biol Ther 2002 : We now show that XPC is induced in a variety of human cell lines in response to both ionizing and ultra-violet ( UV ) radiation and alkylating agents, and that this induction requires wild-type p53
Adimoolam et al., Proc Natl Acad Sci U S A 2002 : Furthermore, regulated expression of wild-type p53 in p53 null Li-Fraumeni syndrome human fibroblasts significantly augmented the expression of XPC protein
Ford et al., Mutat Res 2005 : The mechanisms involved in this process include both transcriptional and post-translational regulation by p53 of the DDB2 and XPC gene products, two critical DNA damage recognition proteins required for GGR
Hardy et al., Anticancer Res 2010 (Bone Neoplasms...) : The p53 tumor suppressor pathway regulates the G ( 1 ) /S checkpoint by regulating the cyclin dependent kinase inhibitor p21 ( Waf1/Cip1 ), but p53 also regulates the nucleotide excision DNA repair protein XPC