Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
NFE2L2
→
BACH1
(decreases, BACH1 Activity, NFE2L2 Activity)
Evidence: Bach1 competes with activators, including Nrf2, for the binding to Maf recognition element (MARE). HREs share a nucleotide sequence with the MARE, which is important in development and differentiation (Motohashi et al., 1997; Ogawa et al., 2001). Therefore, stress response genes bearing MARE may be up-regulated via the MARE-binding transcription factors with increased levels of heme (Ogawa et al., 2001).
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *