Hong et al., J Virol 2002
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Indeed, high concentrations of cyanovirin dramatically enhanced gp120-Fc binding to cell surfaces in the presence or absence of DC-SIGN Lekkerkerker et al., Virology 2004
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Furthermore, we demonstrate that DC-SIGN binding to gp120 enhanced CD4 binding, suggesting that DC-SIGN induces conformational changes in gp120 , which may provide new targets for neutralizing antibodies