Gene interactions and pathways from curated databases and text-mining

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ACE — NOX1

Text-mined interactions from Literome

Suda et al., J Pharmacol Sci 2006 (Hypertension) : The increase in bradykinin concentration may be involved in the enhancing effect of the ACE inhibitor on NOx production in vivo
Jin et al., PloS one 2012 (Inflammation) : Furthermore, ACE2 deficiency led to greater increases in Ang II-mediated profilin-1 expression, NADPH oxidase activity, and superoxide and peroxynitrite production in the aortas of ACE2KO mice associated with enhanced phosphorylated levels of Akt, p70S6 kinase, extracellular signal regulated kinases ( ERK1/2 ) and endothelial nitric oxide synthase (eNOS)