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ACE — NOX1
Text-mined interactions from Literome
Suda et al., J Pharmacol Sci 2006
(Hypertension) :
The increase in bradykinin concentration may be involved in the enhancing
effect of the
ACE inhibitor on
NOx production in vivo
Jin et al., PloS one 2012
(Inflammation) :
Furthermore,
ACE2 deficiency
led to greater increases in Ang II-mediated profilin-1 expression,
NADPH oxidase activity, and superoxide and peroxynitrite production in the aortas of ACE2KO mice associated with enhanced phosphorylated levels of Akt, p70S6 kinase, extracellular signal regulated kinases ( ERK1/2 ) and endothelial nitric oxide synthase (eNOS)