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PTPN11 — SST

Text-mined interactions from Literome

Florio et al., J Physiol Paris 2000 (MAP Kinase Signaling System) : Thus, the activation of SHP-2 by SSTR1 may mediate the antiproliferative activity of somatostatin
Florio et al., Mol Endocrinol 2001 : Conversely, no differences in somatostatin stimulated SHP-2 activity, ( approximately +50 %, P < 0.05 ), were observed among all the cell lines
Ferjoux et al., Mol Biol Cell 2003 : Critical role of Src and SHP-2 in sst2 somatostatin receptor mediated activation of SHP-1 and inhibition of cell proliferation
Arena et al., Mol Endocrinol 2007 : In response to SST , JAK2 is activated in a G protein dependent manner, dissociates from and phosphorylates SHP-2 , increasing its activity