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EPHB2 — RUNX1

Text-mined interactions from Literome

Hamelin et al., Blood 2006 : Thrombopoietin regulates IEX-1 gene expression through ERK induced AML1 phosphorylation ... Here we show that the regulation of the immediate early gene X-1 ( IEX-1 ), identified as an ERK substrate in response to TPO, was mediated by an ERK dependent phosphorylation of AML1 ... Taken together, these data suggest that AML1 plays a role in modulating the IEX-1 expression and that the ERK dependent AML1 phosphorylation regulates the TPO mediated activation of IEX-1
Phimphilai et al., J Bone Miner Res 2006 : However, RUNX2 did not increase the ability of this BMP to activate SMAD, ERK , p38, and JNK pathways