CarĂ³n et al., Mol Cancer Ther 2005
(Carcinoma...) :
Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1 , and AKT and the effect of therapeutic kinase inhibitors on cell survival
Wang et al., Cancer Res 2013
(Breast Neoplasms...) :
In addition, Pdk1 activation of the downstream effector p90RSK is also increased by the combined presence of mutant KRAS and PIK3CA