Gene interactions and pathways from curated databases and text-mining

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SERPINE2 — TNF

Text-mined interactions from Literome

Mbebi et al., J Cell Physiol 1999 : Protease nexin I secretion is stimulated by tumor necrosis factor-alpha , transforming growth factor-beta and interleukin-1 ... Secreted protease nexin I-thrombin complex was enhanced in the presence of transforming growth factor-beta and tumor necrosis factor-alpha
Kasza et al., Cytokine 2001 (Astrocytoma) : We have examined expression of the components of the plasminogen activation system in human astrocytoma U373-MG cells and found that interleukin 1beta (IL-1beta), tumour necrosis factor alpha TNF-alpha ), interferon gamma (INF-gamma) and epidermal growth factor (EGF) specifically regulate the expression of tissue-type plasminogen activator ( t-PA ), urokinase-type plasminogen activator ( u-PA ), plasminogen activator inhibitor type 1 ( PAI-1 ) and protease nexin-1 (PN-1)
Suzuki et al., FEBS Lett 2006 : Here, we investigated whether tumor necrosis factor alpha-(TNF-alpha) induced expression of SerpinE2 is mediated by the nuclear factor-kappaB (NF-kappaB) p65 subunit ... These results indicated that activation of NF-kappaB p65 plays an important role in TNF-alpha induced expression of SerpinE2
Vaughan et al., J Biol Chem 1993 (Brain Neoplasms...) : Interleukin-1, tumor necrosis factor-alpha , and transforming growth factor-beta stimulated the secretion of PN-1 by the neuroblastoma cell line SK-N-SH