◀ Back to TNF

TIRAP — TNF

Text-mined interactions from Literome

Andreakos et al., Blood 2004 : In contrast, in macrophages neither MyD88, Mal/TIRAP , nor I kappa B kinase 2 (IKK2) are required for NF-kappa B activation or tumor necrosis factor alpha (TNF alpha) , IL-6, or IL-8 production, although Mal/TIRAP is still involved in the production of interferon beta (IFN beta)
Sacre et al., Am J Pathol 2007 (Arthritis, Rheumatoid...) : In addition, overexpression of dominant negative forms of MyD88 and Mal/TIRAP significantly down-regulated the spontaneous production of cytokines tumor necrosis factor-alpha , IL-6, and vascular endothelial growth factor, and enzymes MMP-1, MMP-2, MMP-3, and MMP-13 in RA synovial membrane cell cultures