Hartman et al., Nat Genet 2002
(Breast Neoplasms) :
Here we show that BRCA1 specifically enhances the GGR pathway, independent of p53, and can induce p53 independent expression of the NER genes XPC , DDB2, and GADD45
El-Deiry et al., Cancer Biol Ther 2002
(Breast Neoplasms...) :
There is some controversy regarding the precise mechanism of upregulation of XPE DDB2 or XPC by BRCA1 , with some evidence suggesting that p53 is involved in their regulation