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CASP3 — RAD51
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Huang et al., Mol Cell Biol 1999
:
Role for
caspase mediated cleavage of
Rad51 in induction of apoptosis by DNA damage
Flygare et al., Eur J Biochem 2000
(Adenocarcinoma...) :
Caspase-3 mediated cleavage of
HsRad51 at an unconventional site
Broustas et al., J Biol Chem 2004
(Prostatic Neoplasms) :
BRCC2 , a novel BH3-like domain containing protein, induces apoptosis in a
caspase dependent manner
Kim et al., Autophagy 2008
(Disease Models, Animal...) :
To test this hypothesis, combinations of Z-DEVD (
caspase-3 inhibitor ),
RAD001 ( mTOR inhibitor ) and irradiation were tested in cell and mouse models
Brown et al., Radiat Res 2008
:
We further showed that caspase 3 cleavage of
Rad51 resulted in a functional decrease in Rad51 strand exchange activity and that inhibition of
caspase 3 activity
increased Rad51 protein levels and Rad51 foci
Wu et al., Evidence-based complementary and alternative medicine : eCAM 2013
:
Compared to FIS treatment alone of COLO205 cells, GA and
RAD significantly enhanced FIS induced cytotoxicity,
increased expression of cleaved
caspase-3 and the PAPR protein, and produced a greater density of DNA ladder formation