Gene interactions and pathways from curated databases and text-mining

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ANGPT2 — KLF5

Text-mined interactions from Literome

Bafford et al., Surgery 2006 (Hyperplasia) : Stimulation of VSMC with Ang II and TNF-alpha led to a rapid upregulation of KLF5 expression, and a later increase in SVV, which was cell-cycle independent
Gao et al., Biol Pharm Bull 2006 : In this study, we showed that in growth arrested vascular smooth muscle cells ( VSMCs ), Ang II induced cell proliferation, KLF5 mRNA and protein expression in a dose- and time dependent fashion, whereas KLF5 mRNA stability was not affected ... These data, for the first time, revealed the involvements of some intracellular signals in the regulation of KLF5 expression in response to Ang II in VSMCs and showed the possible role of KLF5 in Ang II-induced cell proliferation in VSMCs