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PTEN — SETD2

Text-mined interactions from Literome

Emerling et al., Proc Natl Acad Sci U S A 2008 : Here, we show that the loss of PTEN increases the transcriptional activity of hypoxia-inducible factor 1 (HIF-1) through the inactivation of Forkhead transcription factors ( FOXO ) in PTEN-null cells
Tian et al., Carcinogenesis 2010 (Carcinoma, Hepatocellular...) : Overexpression of PTEN in HepG2 cells resulted in the downregulation of proliferation and migration of cocultured endothelial cells and decreased expression of hypoxia-inducible factor 1 (HIF-1) and VEGF
Paweł et al., Lipids 2013 (Leiomyoma...) : Additionally, in uterine leiomyomas we found relevant activation of both PTEN and MAPK(ERK1/2) signaling pathways with only a minor change in AKT activity and relatively absent HIF-1a/AMPK activation