Gene interactions and pathways from curated databases and text-mining

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CASP3 — PPT1

Text-mined interactions from Literome

Cho et al., J Neurochem 2000 (Neuroblastoma) : Overexpression of PPT1 inhibited this C2-ceramide- or LY294002 mediated activation of caspase-3 by 50 %
Kim et al., Hum Mol Genet 2006 (Nerve Degeneration...) : Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL