Gene interactions and pathways from curated databases and text-mining

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GPI — NOS2

Text-mined interactions from Literome

Tetsuka et al., Proc Natl Acad Sci U S A 1994 : These data suggest that ( i ) endogenous PGE2 downregulates iNOS induction, ( ii ) this inhibitory effect of PGE2 on iNOS induction is not mediated by activation of adenylate cyclase, and ( iii ) exogenous PGI2 stimulates COX induction possibly by activation of adenylate cyclase
Tachado et al., J Immunol 1996 : Purified malarial GPI is sufficient to induce NO release in a time- and dose dependent manner in macrophages and vascular endothelial cells, and regulates inducible NO synthase expression in macrophages