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ATP5O — TET3
Text-mined interactions from Literome
He et al., Acta Pharmacol Sin 2002
:
The basal P-gp
ATPase activity was
increased by verapamil ( Ver ), vincristine ( VCR ), doxorubicin ( Dox ),
tetrandrine ( Tet ) , dauricine ( DRC ), berbamine ( BBM ), and daurisoline ( DRS ), with respective half-maximal activity concentrations Km of about 17, 5.9, 41, 2.3, 11, 23, and 22 micromol/L. Berberine ( BBR ) produced a relatively slight activation
Rao et al., Acta Pharmacol Sin 2002
(Ventricular Remodeling) :
Tet improved haemodynamic changes during remodeling special diastolic function such as LV compliance and stiffness,
increased cardiac myosin
ATPase activity and Na+-K+, Ca2+ ATPase activity, and normalized vascular reactivity
Qiu et al., World J Gastroenterol 2004
(Acute Disease...) :
To study the change of intracellular calcium-magnesium ATPase ( Ca ( 2+ ) -Mg ( 2+ ) -ATPase ) activity in pancreas, liver and kidney tissues of rats with acute pancreatitis ( AP ), and to investigate the
effects of Qingyitang ( QYT ) ( Decoction for clearing the pancreas ) and
tetrandrine ( Tet ) and vitamin E ( VitE ) on the activity of Ca ( 2+ ) -Mg ( 2+ )
-ATPase
Chen et al., Yao Xue Xue Bao 1991
:
The
effect of
tetrandrine ( Tet ) on Na+, K ( + )
-ATPase and Mg ( 2+ ) -ATPase in rat myocardial microsomes was investigated in vitro ... Under optimal condition,
Tet did not influence Na+, K ( + ) -ATPase activity but concentration-dependently
inhibited Mg ( 2+ )
-ATPase with an IC50 of 179 mumol/L ... A kinetic analysis showed that
Tet increased the affinity of Na+, K ( + )
-ATPase to ATP, but did not change the maximal velocity of the enzyme reaction
Yallapragada et al., J Toxicol Environ Health 1991
(Body Weight) :
TET and TMT
inhibited Ca ( 2+ )
-ATPase in a dose dependent manner but TBT exhibited its inhibitory effect only at the highest dose ( 2.5 mg/kg/d )
Stine et al., Toxicol Appl Pharmacol 1988
:
At 10 days of age, following the onset of myelination, the IC50 for
TET inhibition of brain mitochondrial
ATPase increased to 71 microM