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CXCR3 — IL4

Text-mined interactions from Literome

Kim et al., J Immunol 2003 : IL-4 enhances the generation of CCR4 ( + ) and CRTH2 ( + ) T cells, and suppresses the generation of CXCR3 ( + ) T cells and CCR7 ( - ) T cells, while IL-12 suppresses the level of CCR4 in responding T cells
Barbi et al., J Immunol 2008 (Genetic Predisposition to Disease...) : Impaired induction of CXCR3 on BALB/c T cells was not due to lack of IFN-gamma and was mediated partially by IL-10 but not IL-4 or IL-13
Jiang et al., Chin Med J (Engl) 2009 (Embryo Loss) : Expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4 ( + ) T cells in CBA/JxDBA/2 mouse model, selectively induced by IL-4 and IL-10, regulates the embryo resorption rate ... This study aimed to observe whether IL-4 and IL-10 may regulate the expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4 ( + ) T cells in CBA/JxDBA/2 mouse model and to explore the role of CCR3, CCR5, CXCR3 in immune tolerance in pregnancy ... The pregnancy immune tolerance may be induced through selective induction of CCR3, CCR5 and CXCR3 expressions by IL-4 together with IL-10
Schmitz et al., Brain Behav Immun 2013 : Oppositely, CXCR3-deficiency had no protective effect after traumatic nerve injury but reduced EAE evoked hyperalgesia and was associated with reduced clinical EAE scores, a reduction of the pro-inflammatory cell infiltration and reduced upregulation of interferon gamma and interleukin-17 in the spinal cord