Gene interactions and pathways from curated databases and text-mining

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APC — CD8A

Text-mined interactions from Literome

Cho et al., J Immunol 2001 : In this study, we demonstrated that non-APC-specific gene expressions induced significant CD8 ( + ) CTL and IFN-gamma producing cells and Ab responses, whereas APC-specific gene expressions led to moderate CTL and IFN-gamma-producers, but no Ab responses
Ndhlovu et al., Proc Natl Acad Sci U S A 2010 : We conclude that CD8 ( + ) T cells are heterogeneous in their functionality and that this is dependent , in a dynamic way, on the stimulating APC
Brignone et al., Journal of translational medicine 2010 (Breast Neoplasms...) : Blood samples were taken 13 days after the sixth and the twelfth IMP321 injections to determine sustained APC , NK and memory CD8 T cell responses
Cai et al., J Exp Med 1994 : These findings, together with experiments with heterozygous vs. homozygous stimulator cells, suggest that HI and HD responses reflect differences in the overall avidity of T antigen presenting cell (APC) interaction : high-avidity interaction leads to strong intracellular signaling and an HI response, whereas low-avidity interaction causes weak signaling and an HD response ; high-avidity T/APC interaction is heavily dependent on CD8 expression
Schnyder et al., J Clin Invest 1997 (Cell Transformation, Viral...) : The stimulation of four CD4 ( + ) and two CD8 ( + ) sulfamethoxazole-specific T cell clones by different antigen presenting cells (APC) was measured both by proliferation and cytolytic assays