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ANGPT2 — NOS1
Text-mined interactions from Literome
Moreno et al., Am J Physiol Regul Integr Comp Physiol 2002
:
The aim of this study was to assess the
effects of acute or prolonged increases of
ANG II on
nitric oxide synthase (NOS) activities and protein expression in mesenteric resistance vessels, left ventricle, renal cortex, and renal medulla ... Acute
ANG II infusion
increased ( P < 0.05 ) Ca2+ dependent
NOS activity in renal cortex and renal medulla ( 81 +/- 18 and 611 +/- 48, respectively ), but no differences were found in mesenteric arteries and left ventricle with respect to control rats
Campese et al., Hypertension 2002
:
This raises the possibility that the stimulatory effects of
Ang II on central SNS activity may be
mediated by inhibition of
nNOS and IL-1beta ... In conclusion, these studies suggest that
Ang II inhibits the expression of IL-1beta and
nNOS in the brain
Fernandez et al., Hypertension 2005
:
In Ca ( 2+ ) -loaded neurons,
Ang II-induced decreases in [ Ca ( 2+ ) ] i were
attenuated by phospholipase C inhibition ( U73122 ) or
nitric oxide ( NO ) synthase inhibition ( L-NMMA ) and were mimicked by the cGMP analogue 8-Br-cGMP
Ratliff et al., Pediatr Res 2010
:
ANG II regulates nNOS and eNOS expression and
NOS activity in afferent arterioles of the developing kidney via AT1 and AT2 receptors
Kim et al., Am J Physiol Endocrinol Metab 2012
:
Activation of mTOR/p70S6 kinase by
ANG II inhibits insulin stimulated endothelial
nitric oxide synthase and vasodilation
Boulanger et al., Circ Res 1998
(Hypertension) :
In further support of
NOS activation by
Ang II in nonendothelial cells, Ang II but not acetylcholine stimulated cGMP levels by 2-fold in SHR arteries without endothelium ; nitro-L-arginine decreased both basal and Ang II-stimulated cGMP levels