Gene interactions and pathways from curated databases and text-mining

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ANGPT2 — NOS2

Text-mined interactions from Literome

Wolf et al., J Am Soc Nephrol 1997 : Western blot analysis applying a specific monoclonal antibody generated against mouse iNOS revealed that 10 ( -8 ) -10 ( -6 ) M ANG II significantly reduced LPS/gamma-IF induced iNOS protein expression
Fernandez et al., Hypertension 2005 : In Ca ( 2+ ) -loaded neurons, Ang II-induced decreases in [ Ca ( 2+ ) ] i were attenuated by phospholipase C inhibition ( U73122 ) or nitric oxide ( NO ) synthase inhibition ( L-NMMA ) and were mimicked by the cGMP analogue 8-Br-cGMP
Kim et al., Am J Physiol Endocrinol Metab 2012 : Activation of mTOR/p70S6 kinase by ANG II inhibits insulin stimulated endothelial nitric oxide synthase and vasodilation
Ikeda et al., Circulation 1995 (Second Messenger Systems) : These results indicate that Ang II upregulates IL-1 beta induced iNOS expression in cardiac myocytes, which is mediated at least partially via activation of protein kinase C
Yanagisawa et al., Toxicol Appl Pharmacol 1998 (Acute Kidney Injury...) : In HgCl2 induced ARF, the gene expression of ET-1 or iNOS is at least in part up-regulated at the transcription level by endogenous ANG II or TNF