Gene interactions and pathways from curated databases and text-mining

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IFI27 — MAP2K1

Text-mined interactions from Literome

Hoshino et al., J Biol Chem 2001 (Neoplasms) : Overexpression in RPMI-SE cells of either a kinase negative form of MEK1 or wild-type MAP kinase phosphatase-3 also induced up-regulation of p27 ( Kip1 )
Zhang et al., J Biol Chem 2008 : Parallel to cell death processes, overexpression of p21 or p27 profoundly enhanced DCA + MEK1/2 inhibitor induced expression of ATG5 and GRP78/BiP and phosphorylation of PKR-like endoplasmic reticulum kinase ( PERK ) and eIF2alpha, and it increased the numbers of vesicles containing a transfected LC3-GFP construct
Ding et al., J Gastroenterol Hepatol 2008 (Helicobacter Infections...) : MEK1/2 inhibition increased p21, p27 and cyclin E and JNK inhibition additionally increased cyclin D1 expression