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EPHB2 — IRF3

Text-mined interactions from Literome

Balaraman et al., Biochem Biophys Res Commun 2004 : The use of inhibitors selective for ERK ( PD98059 ) and p38 ( SB203580 ) mitogen activated protein ( MAP ) kinase pathway showed that preincubation of cells with either SB203580 or PD98059 did not affect the binding activity of IRF-E, suggesting that both p38 and ERK MAP kinase activation are not necessary for IRF-E activation
Harii et al., Mol Endocrinol 2005 (Thyroiditis, Autoimmune...) : In this report, we demonstrate TLR3 mRNA and protein are expressed on Fisher rat thyroid cell line-5 ( FRTL-5 ) thyroid cells and are functional because incubating cells with polyinosine-polycytidylic acid causes 1 ) transcriptional activation of both the nuclear factor kappaB (NF-kappaB)/Elk1 and interferon (IFN) regulatory factor-3/IFN-beta signal paths, 2 ) posttranscriptional activation of NF-kappaB and ERK1/2 , and 3 ) increased IFN-beta mRNA
Peirce et al., PloS one 2010 : Moreover, LPS induced activation of the MAP kinases ERK and p38 was enhanced in cells over expressing Themis2 whereas the activation of JNK, IRF3 or NF-kappaB p65, was unaffected
Lu et al., Basic Res Cardiol 2013 (Cardiomegaly...) : Mechanistically, we discovered that IRF3 interacted with ERK2 and thereby inhibited the ERK1/2 signaling