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EHMT1 — EPHB2
Text-mined interactions from Literome
Koehler et al., Mol Endocrinol 2005
:
GLP-2 increased cAMP accumulation and
activated ERK1/2 in HeLa cells transiently expressing the cloned human HeLa cell GLP-2R cDNA
Estall et al., J Biol Chem 2005
:
The majority of the C-terminal receptor tail was dispensable for
GLP-2 induced cAMP accumulation,
ERK1/2 activation, and endocytosis in transfected cells
Syme et al., Mol Endocrinol 2006
:
Finally,
GLP-1R stimulated activation of
ERK1/2 , which involves transactivation of epidermal growth factor receptors, required lipid raft integrity
Lagoumintzis et al., Scand J Immunol 2008
(Pseudomonas Infections) :
Activation of both p38 and
ERK1/2 induced by P. aeruginosa
slime-GLP was dramatically reduced in the presence of anti-TLR2 and to a lesser degree in the presence of anti-TLR4, whereas the P. aeruginosa-LPS induced stimulation was inhibited only in the presence of anti-TLR4
Angelone et al., Nutr Metab Cardiovasc Dis 2012
(MAP Kinase Signaling System) :
For the first time, to our knowledge, we found that : ( 1 ) the rat heart expresses functional
GLP-2 receptors ; ( 2 ) GLP-2 acts on both myocardium and coronaries, negatively modulating both basal and ß-adrenergic stimulated cardiac performance ; and ( 3 ) GLP-2 effects are mediated by G-proteins and
involve ERK1/2