Gene interactions and pathways from curated databases and text-mining

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CREBBP — IL6

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Ray et al., Mol Endocrinol 2002 : Taken together, our results indicate that IL-6-inducible expression of the hAGT promoter is mediated by physical association of the COOH terminus of STAT3 with p300/CBP , the recruitment of which targets histone acetylation and results in chromatin remodeling
Ueda et al., J Biol Chem 2002 (MAP Kinase Signaling System...) : To date, no one has examined the role of SRC-1 in ligand independent activation of the AR by IL-6 or other signaling pathways known to activate the full-length receptor ... 1 ) SRC-1 similarly enhanced ligand independent activation of the AR by IL-6 to the same magnitude as that obtained via ligand dependent activation