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CD38 — TLR2
Text-mined interactions from Literome
Rozková et al., Int J Cancer 2010
(Leukemia, Lymphocytic, Chronic, B-Cell) :
We report that
TLR stimulation
induces expression of
CD38 , a negative prognostic marker, on B-CLL cells
Hartiala et al., J Immunol 2010
:
The data show that 1 ) effective signaling via p38 MAPK ( and STAT1 and NF-kappaB ) is needed for CD38 expression and 2 )
TLR2 stimulation, as opposed to TLR4 stimulation, does not
induce IFN-beta autocrine loop dependent expression of
CD38 and secretion of IL-12